Description

3H-Pyrrolo[2,3-B]Pyridine-5-Carboxylic Acid, 2,3,3-Trimethyl- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) and serves as a key building block in modern medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug molecules, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the discovery of new bioactive compounds.
• Active Pharmaceutical Ingredient (API) Development: Used in the research and process development stages for creating novel APIs.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis projects and scale-up activities.
• Biochemical Research: May be employed as a specialized reagent or probe in biochemical and pharmacological studies.

Basic Information

Product Name	3H-Pyrrolo[2,3-B]Pyridine-5-Carboxylic Acid, 2,3,3-Trimethyl-
CAS No.	586409-15-6
Molecular Formula	C11H14N2O2
Molecular Weight	206.24 g/mol
Synonyms	2,3,3-Trimethyl-3H-pyrrolo[2,3-b]pyridine-5-carboxylic acid; 2,3,3-Trimethyl-5-carboxy-3H-pyrrolo[2,3-b]pyridine; 3H-Pyrrolo[2,3-b]pyridine-5-carboxylic acid, 2,3,3-trimethyl-; 586409-15-6; 2,3,3-Trimethyl-3H-pyrrolo[2,3-b]pyridine-5-carboxylate (deprotonated form)
EINECS	Contact for details

Quality Control

Our 3H-Pyrrolo[2,3-B]Pyridine-5-Carboxylic Acid, 2,3,3-Trimethyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.