Description

4-Methyl-2-(3-Trifluoromethyl-Phenyl)-Pyridine is a specialized heterocyclic compound featuring a pyridine core substituted with a methyl group and a trifluoromethylphenyl moiety, offering unique electronic and steric properties. This molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for the synthesis of complex organic molecules. It is primarily sought by research institutions and fine chemical manufacturers engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Serves as a crucial precursor for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Used in organometallic chemistry to create specialized ligands for catalytic systems, leveraging the electron-withdrawing trifluoromethyl group to modulate reactivity.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional materials where its aromatic and fluorinated structure can influence electronic properties.
• Chemical Reference Standard: Supplied to analytical laboratories for use as a high-purity standard in method development, quality control, and regulatory testing.

Basic Information

Product Name	4-Methyl-2-(3-Trifluoromethyl-Phenyl)-Pyridine
CAS No.	583052-22-6
Molecular Formula	C13H10F3N
Molecular Weight	237.22 g/mol
Synonyms	2-(3-(Trifluoromethyl)phenyl)-4-methylpyridine; 4-Methyl-2-[3-(trifluoromethyl)phenyl]pyridine; α,α,α-Trifluoro-m-tolyl-4-methyl-2-pyridine; 3-Trifluoromethylphenyl-4-methyl-2-pyridine; 4-Methyl-2-(3-trifluoromethylphenyl)pyridine; 2-(3-Trifluoromethylphenyl)-4-picoline
EINECS	Contact for details

Quality Control

Our production of 4-Methyl-2-(3-Trifluoromethyl-Phenyl)-Pyridine adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified through advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, supporting your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.