Description

Propanedioic Acid, 2-(Acetylamino)-2-[(7-Chloro-1H-Indol-3-Yl)Methyl]-, 1,3-Diethyl Ester is a specialized synthetic intermediate of significant interest in advanced organic synthesis. This compound, with CAS number 582319-05-9, is valued for its unique molecular architecture, which incorporates both indole and malonate ester functionalities. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the construction of complex molecules, particularly in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting neurological or oncological pathways.
• Agrochemical Research: Used in the development of new pesticides or herbicides, leveraging the bioactive indole core structure.
• Chemical Biology Probe Synthesis: Employed in the creation of specialized molecular probes for studying enzyme function or protein interactions.
• Organic Material Precursor: Acts as a monomer or intermediate in the research of advanced organic electronic materials or specialty polymers.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for methodological development and discovery chemistry projects.

Basic Information

Product Name	Propanedioic Acid, 2-(Acetylamino)-2-[(7-Chloro-1H-Indol-3-Yl)Methyl]-, 1,3-Diethyl Ester
CAS No.	582319-05-9
Molecular Formula	C19H21ClN2O5
Molecular Weight	392.84 g/mol
Synonyms	2-Acetamido-2-[(7-chloro-1H-indol-3-yl)methyl]propanedioic acid diethyl ester; Diethyl 2-acetamido-2-[(7-chloro-1H-indol-3-yl)methyl]malonate; 1,3-Diethyl 2-(acetylamino)-2-[(7-chloro-1H-indol-3-yl)methyl]propanedioate; 2-[(7-Chloro-1H-indol-3-yl)methyl]-2-(acetylamino)malonic acid diethyl ester; N-Acetyl-α-(7-chloro-1H-indol-3-ylmethyl)malonic acid diethyl ester; AKOS BRN 0972; ZINC000257019509
EINECS	Contact for details

Quality Control

Every batch of this high-value intermediate is produced and analyzed under strict quality management protocols to ensure consistency and purity for sensitive research applications. Standard quality assurance includes identity confirmation by spectroscopic methods (NMR, IR) and purity determination by HPLC. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.