Description

4-Isocyanato-1H-Indole is a versatile and highly reactive indole-based isocyanate building block, essential for the synthesis of complex heterocyclic compounds. Its core value lies in enabling the precise introduction of the isocyanate functional group into indole scaffolds, facilitating the creation of novel molecular architectures. This compound is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel indole-based drug candidates, including kinase inhibitors and receptor modulators.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators with indole cores.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for producing specialty polyurethanes and polyurea coatings with unique properties.
• Chemical Biology: Employed in the design of activity-based probes and affinity labels for studying enzyme mechanisms and protein function.
• Material Science: Facilitates the creation of advanced functional materials, such as sensors and conductive polymers, via its reactive isocyanate group.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring tailored indole derivatives.

Basic Information

Product Name	4-Isocyanato-1H-Indole
CAS No.	581812-74-0
Molecular Formula	C9H6N2O
Molecular Weight	158.16 g/mol
Synonyms	1H-Indole-4-isocyanate; 4-Isocyanatoindole; 4-Indolyl isocyanate; Isocyanic acid 1H-indol-4-yl ester; 4-Isocyanato-1H-indole; 581812-74-0; 4-Indole isocyanate
EINECS	Contact for details

Quality Control

Our 4-Isocyanato-1H-Indole is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its moisture-sensitive (hygroscopic) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.