Description

2-(Dimethylamino)Pyridine-5-Boronic Acid Hydrate is a versatile and highly valuable organoboron building block, specifically a pyridine-substituted boronic acid derivative. Its core value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable synthetic intermediates for drug discovery, catalyst development, and specialty polymer synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its role in creating complex heterocyclic structures.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated ligands used in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs and conductive polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme inhibition.
• Custom Synthesis and Contract Manufacturing: A critical reagent for custom synthesis houses and CROs/CMOs serving the global life sciences industry.

Basic Information

Product Name	2-(Dimethylamino)Pyridine-5-Boronic Acid Hydrate
CAS No.	579525-46-5
Molecular Formula	C7H11BN2O2 · xH2O
Molecular Weight	153.99 (Anhydrous basis)
Synonyms	5-(Dimethylamino)pyridine-2-boronic acid hydrate; 2-Borono-5-(dimethylamino)pyridine hydrate; (5-(Dimethylamino)pyridin-2-yl)boronic acid hydrate; DMAP-Boronic Acid Hydrate; 2-(N,N-Dimethylamino)pyridine-5-boronic acid hydrate; 2-Pyridineboronic acid, 5-(dimethylamino)-, hydrate
EINECS	Contact for details

Quality Control

Every batch of 2-(Dimethylamino)Pyridine-5-Boronic Acid Hydrate is produced and tested under strict quality management systems. We ensure compliance with relevant industry standards for fine chemicals and pharmaceutical intermediates. Comprehensive analytical testing, including HPLC, NMR, and elemental analysis, is performed to verify identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and meet your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. For long-term storage, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥95.0% (Anhydrous basis)
Water Content (KF)	≤5.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.