Description

5-Bromo-2-Cyclopropylpyridine is a high-value brominated pyridine derivative, serving as a critical building block in modern synthetic chemistry. Its unique structure, featuring a cyclopropyl ring adjacent to the pyridine nitrogen, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyridine and cyclopropyl motifs.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating novel ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Material Science Research: Building block for the development of organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probes: Utilized in medicinal chemistry to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and scaled-up processes.

Basic Information

Product Name	5-Bromo-2-Cyclopropylpyridine
CAS No.	579475-29-9
Molecular Formula	C8H8BrN
Molecular Weight	198.06 g/mol
Synonyms	2-Cyclopropyl-5-bromopyridine; 5-Bromo-2-cyclopropylpyridine; 5-Bromo-2-cyclopropyl-pyridine; Pyridine, 5-bromo-2-cyclopropyl-; 2-(5-Bromopyridin-2-yl)cyclopropane
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Cyclopropylpyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.