Description

5H-Cyclopenta[B]Pyridine-3-Carbonitrile,2-Amino-6,7-Dihydro-4-(3-Pyridinyl)-(9Ci) is a high-purity, heterocyclic organic compound with the CAS number 579441-22-8, serving as a critical advanced intermediate in modern pharmaceutical and agrochemical research. Its complex fused-ring structure makes it a valuable scaffold for developing novel active ingredients, particularly in kinase inhibitor programs and crop protection agents. This compound is essential for R&D chemists and process development scientists in the life sciences sector seeking to build molecular complexity and explore new chemical spaces.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel small-molecule drug candidates, especially in oncology and CNS therapeutic areas.
• Kinase Inhibitor Precursor: Used in the research and development of protein kinase inhibitors due to its privileged pyridine-based heterocyclic core.
• Agrochemical Synthesis: Serves as an intermediate in creating new generations of herbicides and insecticides with enhanced efficacy and selectivity.
• Chemical Biology Probe Development: Utilized in academic and industrial labs to create tool compounds for studying biological pathways and target validation.
• Material Science Research: Investigated as a precursor for organic electronic materials and ligands in catalytic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical companies for bespoke synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	5H-Cyclopenta[B]Pyridine-3-Carbonitrile,2-Amino-6,7-Dihydro-4-(3-Pyridinyl)-(9Ci)
CAS No.	579441-22-8
Molecular Formula	C14H12N4
Molecular Weight	236.28 g/mol
Synonyms	2-Amino-4-(pyridin-3-yl)-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carbonitrile; 2-Amino-4-(3-pyridinyl)-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carbonitrile; 579441-22-8; 3-Pyridinecarbonitrile, 2-amino-4,5,6,7-tetrahydro-4-(3-pyridinyl)-; 2-Amino-4-(3-pyridyl)-4,5,6,7-tetrahydrocyclopenta[b]pyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced under strict quality management systems. We employ state-of-the-art analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.