Description

1-Oxaspiro[2.3]Hexane-5-Carboxylicacid,Methylester,trans-(9Ci) is a specialized spirocyclic oxirane derivative that serves as a valuable chiral building block in advanced organic synthesis. Its unique strained ring system and defined stereochemistry make it a critical intermediate for constructing complex molecular architectures with high precision. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its spirocyclic structure can contribute to unique biological activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Material Science Research: Investigated as a monomer or cross-linking agent for developing polymers with specific thermal or mechanical properties due to its reactive oxirane ring.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fragrance molecules, flavors, and other high-value specialty chemicals.

Basic Information

Product Name	1-Oxaspiro[2.3]Hexane-5-Carboxylicacid,Methylester,trans-(9Ci)
CAS No.	578715-80-7
Molecular Formula	C8H12O3
Molecular Weight	156.18 g/mol
Synonyms	trans-Methyl 1-oxaspiro[2.3]hexane-5-carboxylate; Methyl trans-1-oxaspiro[2.3]hexane-5-carboxylate; trans-5-(Methoxycarbonyl)-1-oxaspiro[2.3]hexane; (1R,5S)-1-Oxaspiro[2.3]hexane-5-carboxylic acid methyl ester; (1S,5R)-1-Oxaspiro[2.3]hexane-5-carboxylic acid methyl ester; Spiro[oxirane-2,1'-cyclopropane]-5-carboxylic acid, 5-methyl ester, trans-; 578715-80-7
EINECS	Contact for details

Quality Control

Our production of 1-Oxaspiro[2.3]Hexane-5-Carboxylicacid,Methylester,trans-(9Ci) adheres to stringent quality management systems to ensure batch-to-batch consistency and high purity for research and scale-up applications. All materials are characterized by advanced analytical techniques including GC, HPLC, NMR, and chiral analysis to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all relevant specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.