Description

2-Amino-6-Iodo-[1,8]Naphthyridine-3-Carbonitrile is a high-purity, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and material science. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other biological pathways where the naphthyridine scaffold is relevant.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its unique halogenated heterocyclic structure.
• Material Science: Acts as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme functions.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create more complex derivatives.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis or metal complexation studies.

Basic Information

Product Name	2-Amino-6-Iodo-[1,8]Naphthyridine-3-Carbonitrile
CAS No.	578007-69-9
Molecular Formula	C9H5IN4
Molecular Weight	312.07 g/mol
Synonyms	6-Iodo-2-amino-[1,8]naphthyridine-3-carbonitrile; 2-Amino-6-iodo-1,8-naphthyridine-3-carbonitrile; 3-Cyano-6-iodo-1,8-naphthyridin-2-amine; 578007-69-9; 6-Iodo-2-amino[1,8]naphthyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, related substances, and residual solvents are available upon request. We adhere to strict quality management protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C for long-term stability. The compound should be kept under an inert atmosphere if specified for the specific grade to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Related Substances (HPLC)	≤ 5.0% total
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.