Description

2-Amino-[1,8]Naphthyridine-3-Carboxylic Acid Hydrochloride is a high-purity, heterocyclic carboxylic acid derivative, primarily utilized as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty fine chemicals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or central nervous system disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging the naphthyridine core's biological activity.
• Ligand Synthesis: Serves as a starting material for creating complex chelating ligands used in catalysis or metal-organic frameworks (MOFs).
• Material Science: Potential building block for organic electronic materials, dyes, or pigments due to its conjugated aromatic system.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and exploratory synthetic chemistry projects.
• Fine Chemical Production: Intermediate in the multi-step synthesis of specialty chemicals for various high-value industrial applications.

Basic Information

Product Name	2-Amino-[1,8]Naphthyridine-3-Carboxylic Acid Hydrochloride
CAS No.	578007-68-8
Molecular Formula	C9H8N3O2 • HCl
Molecular Weight	223.64 g/mol (Free base: 188.18 g/mol)
Synonyms	2-Amino-1,8-naphthyridine-3-carboxylic acid hydrochloride; 3-Carboxy-1,8-naphthyridin-2-amine hydrochloride; 1,8-Naphthyridine-3-carboxylic acid, 2-amino-, hydrochloride; 2-Amino[1,8]naphthyridine-3-carboxylic acid HCl; 578007-68-8; 2-Amino-1,8-naphthyridine-3-carboxylic acid monohydrochloride
EINECS	Contact for details

Quality Control

Our 2-Amino-[1,8]Naphthyridine-3-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, residual solvents, and other critical parameters is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.