Description

2-Amino-5-Iodo-Pyridine-3-Carbaldehyde is a versatile and highly functionalized pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino and an aldehyde group on an iodinated pyridine ring, makes it a valuable precursor for constructing complex heterocyclic systems and pharmaceutical intermediates. This compound is primarily sought after by research institutions and chemical manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Building block for developing new generation herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Used to create sophisticated ligands for transition metal catalysis and organocatalysts.
• Material Science Research: Serves as a monomer or functional unit in the development of organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological processes.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).

Basic Information

Product Name	2-Amino-5-Iodo-Pyridine-3-Carbaldehyde
CAS No.	578007-67-7
Molecular Formula	C6H5IN2O
Molecular Weight	248.02 g/mol
Synonyms	5-Iodo-2-aminopyridine-3-carboxaldehyde; 3-Formyl-5-iodopyridin-2-amine; 2-Amino-5-iodonicotinaldehyde; 5-Iodo-2-aminonicotinaldehyde; 2-Amino-5-iodo-3-pyridinecarboxaldehyde; 578007-67-7; 5-Iodo-2-amino-3-pyridinecarbaldehyde
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Iodo-Pyridine-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.