Description

5-Bromo-3-Iodo-2-Methoxypyridine is a high-purity halogenated pyridine derivative, a crucial building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily sought by R&D chemists and process development scientists for applications in medicinal chemistry, material science, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a building block for creating functionalized ligands, organic semiconductors, and liquid crystal materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi cross-coupling reactions due to the presence of both bromo and iodo substituents.
• Medicinal Chemistry Library Synthesis: Employed in high-throughput screening and combinatorial chemistry to generate diverse compound libraries for drug discovery.
• Chemical Biology Probes: Used to create tagged molecules or probes for studying biological pathways and protein interactions.

Basic Information

Product Name	5-Bromo-3-Iodo-2-Methoxypyridine
CAS No.	578007-66-6
Molecular Formula	C6H5BrINO
Molecular Weight	313.92 g/mol
Synonyms	2-Methoxy-5-bromo-3-iodopyridine; 3-Iodo-5-bromo-2-methoxypyridine; 5-Bromo-3-iodo-2-pyridinol methyl ether; 2-Pyridinol, 5-bromo-3-iodo-, methyl ether; 5-Br-3-I-2-MeOPy; 578007-66-6; SCHEMBL2180621
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Iodo-2-Methoxypyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.