Description

tert-Butyl 4-(1H-Pyrrolo[2,3-B]Pyridin-4-Yl)Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel small-molecule drugs, particularly in oncology and kinase inhibitor research.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) for targeted therapies.
• Kinase Inhibitor Development: Serves as a core scaffold for research and production of protein kinase inhibitors, a major class of oncology drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery pipelines.
• Bioconjugation & Probe Synthesis: The reactive piperazine moiety allows for further functionalization to create labeled compounds for biological testing and diagnostics.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP-scale production of clinical trial materials.

Basic Information

Product Name	tert-Butyl 4-(1H-Pyrrolo[2,3-B]Pyridin-4-Yl)Piperazine-1-Carboxylate
CAS No.	577768-59-3
Molecular Formula	C16H22N4O2
Molecular Weight	302.37 g/mol
Synonyms	4-(1H-Pyrrolo[2,3-b]pyridin-4-yl)piperazine-1-carboxylic acid tert-butyl ester; 1-Boc-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)piperazine; tert-Butyl 4-(1H-pyrrolo[2,3-b]pyridin-4-yl)piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)piperazine; 4-(1H-Pyrrolo[2,3-b]pyridin-4-yl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; BOC-4-(7-Azaindol-4-yl)piperazine; 577768-59-3
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(1H-Pyrrolo[2,3-B]Pyridin-4-Yl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent specifications required for pharmaceutical R&D and cGMP manufacturing. Comprehensive Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.