Description

Ethyl 6-Bromo-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the pyrrolopyridine class of heterocyclic compounds. This compound is a critical building block in modern medicinal chemistry, valued for its versatile reactivity and structural framework. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel small-molecule therapeutics, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors and other biologically active molecules.
• Drug Discovery & Development: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening (HTS) campaigns.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead candidates.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical-stage APIs.
• Academic Research: Employed in university and institutional labs for investigating novel heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	Ethyl 6-Bromo-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylate
CAS No.	577711-94-5
Molecular Formula	C10H9BrN2O2
Molecular Weight	269.10 g/mol
Synonyms	6-Bromo-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid ethyl ester; Ethyl 6-bromo-1H-pyrrolo[2,3-b]pyridine-2-carboxylate; 6-Bromo-1H-pyrrolo[2,3-b]pyridine-2-carboxylate ethyl ester; 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 6-bromo-, ethyl ester; 6-Bromo-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid ethyl ester; 6-Bromo-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid, ethyl ester; Ethyl 6-bromo-7-azaindole-2-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 6-Bromo-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP and ISO standards for pharmaceutical intermediates, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.