Description

Spiro[4.4]Nonan-1-Ol, 6-Amino-, (1S,5S,6S)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its unique spirocyclic structure, featuring both amino and hydroxyl functional groups, makes it a valuable intermediate for constructing complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• As a key chiral intermediate in the research and development of new pharmaceutical candidates, particularly for central nervous system (CNS) and antiviral therapies.
• In the synthesis of advanced agrochemicals, where its rigid spirocyclic scaffold can contribute to novel modes of action and improved environmental profiles.
• For the development of asymmetric catalysts and ligands used in enantioselective synthesis, leveraging its defined stereocenters.
• As a building block in academic and industrial research exploring new chemical space and structure-activity relationships (SAR).
• In the preparation of specialty fine chemicals and high-value materials requiring specific three-dimensional geometry.

Basic Information

Product Name	Spiro[4.4]Nonan-1-Ol, 6-Amino-, (1S,5S,6S)- (9Ci)
CAS No.	575342-92-6
Molecular Formula	C9H17NO
Molecular Weight	155.24 g/mol
Synonyms	(1S,5S,6S)-6-Aminospiro[4.4]nonan-1-ol; (1S,5S,6S)-6-Amino-1-hydroxyspiro[4.4]nonane; 6-Amino-1-hydroxyspiro[4.4]nonane, (1S,5S,6S)-; Spiro[4.4]nonan-1-ol, 6-amino-, (1S,5S,6S)-; (1S,5S,6S)-6-Amino-spiro[4.4]nonane-1-ol; Chiral Spirocyclic Amino Alcohol; CAS 575342-92-6
EINECS	Contact for details

Quality Control

Our production of Spiro[4.4]Nonan-1-Ol, 6-Amino-, (1S,5S,6S)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to meet the exacting standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity (assay), enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.