Description

Ethyl (Tetrahydro-Furan-2-Carbonyl)-Amino-Acetate is a high-purity, versatile chemical intermediate characterized by its unique heterocyclic structure. This compound is essential for synthetic chemists requiring a reactive ester moiety linked to a protected amino acid derivative, facilitating complex molecular construction. It is primarily utilized in the research and development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals, where precise molecular architecture is critical.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Research: Used in developing new-generation herbicides and fungicides with improved efficacy and environmental profiles.
• Peptide Mimetics: Serves as a crucial precursor for creating peptidomimetics and constrained peptides in medicinal chemistry.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Facilitates the development of activity-based probes and molecular tags for studying biological systems.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs engaged in bespoke chemical synthesis projects.

Basic Information

Product Name	Ethyl (Tetrahydro-Furan-2-Carbonyl)-Amino-Acetate
CAS No.	574719-90-7
Molecular Formula	C9H15NO4
Molecular Weight	201.22 g/mol
Synonyms	Ethyl N-(Tetrahydrofuran-2-carbonyl)glycinate; Glycine, N-(tetrahydro-2-furoyl)-, ethyl ester; Ethyl 2-[(Tetrahydro-2-furoyl)amino]acetate; 2-[(Oxolan-2-ylcarbonyl)amino]acetic acid ethyl ester; (Tetrahydrofuran-2-carbonylamino)-acetic acid ethyl ester; Ethyl (THF-2-carbonyl)glycinate; N-(Tetrahydro-2-furoyl)glycine ethyl ester
EINECS	Contact for details

Quality Control

Every batch of Ethyl (Tetrahydro-Furan-2-Carbonyl)-Amino-Acetate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We adhere to cGMP principles where applicable to support our clients in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.