Description

3-Fluoro-5-Nitropicolinonitrile is a high-value, multi-functional heterocyclic building block characterized by its unique combination of fluorine, nitro, and nitrile substituents. This compound matters for its critical role in facilitating rapid and efficient molecular diversification in advanced research and development. It is primarily needed by medicinal chemists and agrochemical researchers for constructing novel active pharmaceutical ingredients (APIs) and crop protection agents, enabling the exploration of new chemical space and the optimization of lead compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Development: Serves as a versatile precursor for creating new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing groups.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and fluorescent tags for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	3-Fluoro-5-Nitropicolinonitrile
CAS No.	573763-02-7
Molecular Formula	C6H2FN3O2
Molecular Weight	167.10 g/mol
Synonyms	5-Nitro-3-fluoropicolinonitrile; 3-Fluoro-5-nitropyridine-2-carbonitrile; 2-Cyano-3-fluoro-5-nitropyridine; 3-Fluoro-5-nitro-2-pyridinecarbonitrile; Picolinonitrile, 3-fluoro-5-nitro-; 3-Fluoro-5-nitropyridine-2-carbonitrile; 2-Pyridinecarbonitrile, 3-fluoro-5-nitro-
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-Nitropicolinonitrile is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to supply chain reliability and documentation transparency supports your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.