Description

2-Nitro-4-(3-Trifluoromethylpyridin-2-Yl)Benzoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique molecular architecture combining a benzoic acid core with nitro and trifluoromethylpyridine substituents. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting complex disease pathways. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers seeking to develop new compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of next-generation herbicides and pesticides, leveraging the biological activity of the pyridine and trifluoromethyl motifs.
• Material Science: Serves as a precursor for functional materials, including liquid crystals and organic semiconductors, due to its conjugated system.
• Chemical Synthesis: Employed in organic synthesis as a versatile scaffold for further functionalization via the carboxylic acid and nitro groups.
• Biochemical Tool Compound: Utilized in biochemical assays and as a probe in pharmacological studies to investigate enzyme inhibition or receptor binding.

Basic Information

Product Name	2-Nitro-4-(3-Trifluoromethylpyridin-2-Yl)Benzoic Acid
CAS No.	573676-07-0
Molecular Formula	C13H7F3N2O4
Molecular Weight	312.20 g/mol
Synonyms	2-Nitro-4-(3-(trifluoromethyl)-2-pyridinyl)benzoic acid; 4-(3-Trifluoromethylpyridin-2-yl)-2-nitrobenzoic acid; Benzoic acid, 2-nitro-4-[3-(trifluoromethyl)-2-pyridinyl]-; 573676-07-0; 2-Nitro-4-(3-trifluoromethyl-2-pyridyl)benzoic acid; 4-(3-(Trifluoromethyl)pyridin-2-yl)-2-nitrobenzoic acid
EINECS	Contact for details

Quality Control

Our 2-Nitro-4-(3-Trifluoromethylpyridin-2-Yl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.