Description

5-Bromo-3-Nitropyridine-2-Carbonitrile is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in providing a versatile scaffold for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials, where its reactive bromo, nitro, and cyano groups enable precise molecular modifications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides.
• Material Science: Serves as a building block for creating functionalized polymers, liquid crystals, and electronic materials.
• Chemical Research: A versatile reagent for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution.
• Dye and Pigment Industry: Employed in the synthesis of specialized heterocyclic dyes and colorants.
• Custom Synthesis: A critical starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.

Basic Information

Product Name	5-Bromo-3-Nitropyridine-2-Carbonitrile
CAS No.	573675-25-9
Molecular Formula	C6H2BrN3O2
Molecular Weight	228.00 g/mol
Synonyms	2-Cyano-5-bromo-3-nitropyridine; 5-Bromo-3-nitro-2-pyridinecarbonitrile; 5-Bromo-3-nitropicolinonitrile; 3-Nitro-5-bromopyridine-2-carbonitrile; 2-Pyridinecarbonitrile, 5-bromo-3-nitro-; Picolinonitrile, 5-bromo-3-nitro-
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Nitropyridine-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.