Description

(3-Bromophenoxy)Triisopropylsilane 97 is a high-purity organosilicon reagent featuring a bromophenoxy functional group protected by a bulky triisopropylsilyl (TIPS) group. This compound matters as a versatile and stable synthetic intermediate, crucial for constructing complex molecules in advanced research and development. It is primarily needed by pharmaceutical, agrochemical, and advanced materials chemists for applications in cross-coupling reactions, nucleophilic substitutions, and as a protected building block in multi-step organic synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key protected synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing substituted phenoxy ethers.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the bromophenoxy moiety is a critical structural component.
• Material Science Research: Acts as a precursor for surface modification, functionalization of silicon-based materials, and in the creation of specialized monomers for polymers.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Nucleophilic Aromatic Substitution: The activated aryl bromide can undergo substitution reactions with various nucleophiles under controlled conditions.
• Ligand and Catalyst Development: Utilized in the preparation of sophisticated ligands and organocatalysts for asymmetric synthesis.
• Organic Electronics: Potential building block for the synthesis of charge-transport materials or emissive layers in OLEDs and other electronic devices.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in laboratory-scale and pilot-scale operations.

Basic Information

Product Name	(3-Bromophenoxy)Triisopropylsilane 97
CAS No.	571202-87-4
Molecular Formula	C15H25BrOSi
Molecular Weight	329.36 g/mol
Synonyms	Triisopropyl(3-bromophenoxy)silane; 3-Bromophenoxytriisopropylsilane; (3-Bromophenoxy)triisopropylsilane; TIPS-O-(3-Bromophenyl); Triisopropylsilyl 3-bromophenyl ether; 1-Bromo-3-(triisopropylsilyloxy)benzene; 3-Bromo-1-(triisopropylsilyloxy)benzene; Silane, triisopropyl(3-bromophenoxy)-
EINECS	Contact for details

Quality Control

Our (3-Bromophenoxy)Triisopropylsilane 97 is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques to confirm identity and assay. Certificates of Analysis (COA) detailing purity, impurities, and physical properties are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.