Description

tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its piperazine and nitropyridine functional groups. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used extensively in research and development for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Serves as a precursor in the development of novel pesticides and herbicides, leveraging its heterocyclic structure.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis services catering to the specific needs of pharmaceutical and biotechnology clients.

Basic Information

Product Name	tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-carboxylate
CAS No.	571189-16-7
Molecular Formula	C14H20N4O4
Molecular Weight	308.33 g/mol
Synonyms	1-Boc-4-(6-Nitro-3-pyridinyl)piperazine; tert-Butyl 4-(6-nitro-3-pyridinyl)-1-piperazinecarboxylate; 1-(tert-Butoxycarbonyl)-4-(6-nitropyridin-3-yl)piperazine; 3-Pyridinecarboxylic acid, 6-nitro-, 4-(1,1-dimethylethoxy)carbonyl-1-piperazinyl ester; 4-(6-Nitropyridin-3-yl)piperazine-1-carboxylic acid tert-butyl ester; BOC-4-(6-Nitropyridin-3-yl)piperazine; 571189-16-7
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.