Description

tert-Butyl 4-(6-Aminopyridin-3-Yl)Piperazine-1-Carboxylate is a high-purity, protected piperazine derivative featuring a key aminopyridine moiety. This compound serves as a versatile and critical pharmaceutical intermediate for the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to build novel nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Kinase Inhibitor Scaffold: Used in medicinal chemistry for constructing potential kinase inhibitors due to its piperazine and aminopyridine structure.
• Agrochemical Research: Serves as a precursor in the development of new herbicides and pesticides with specific biological activity.
• Chemical Biology Probe Synthesis: Employed in creating molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom API synthesis projects.
• Academic & Institutional Research: Used in university and institutional labs for methodological development and novel compound library generation.

Basic Information

Product Name	tert-Butyl 4-(6-Aminopyridin-3-Yl)Piperazine-1-Carboxylate
CAS No.	571188-59-5
Molecular Formula	C14H22N4O2
Molecular Weight	278.35 g/mol
Synonyms	1-Boc-4-(6-Amino-3-pyridyl)piperazine; tert-Butyl 4-(6-amino-3-pyridinyl)-1-piperazinecarboxylate; 4-(6-Aminopyridin-3-yl)piperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(6-aminopyridin-3-yl)piperazine; 3-Pyridinamine, 5-(4-[(1,1-dimethylethoxy)carbonyl]-1-piperazinyl)-; 5-(4-(tert-Butoxycarbonyl)piperazin-1-yl)pyridin-2-amine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(6-Aminopyridin-3-Yl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.