Description

(4-Oxo-3,4,5,6,7,8-Hexahydro-Benzo[4,5]Thieno[2,3-D]Pyrimidin-2-Yl)-Acetonitrile is a high-purity, advanced pharmaceutical intermediate with a complex fused-ring heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily needed by research institutions, custom synthesis laboratories, and pharmaceutical companies engaged in the development of new chemical entities and proprietary drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug molecules targeting various disease pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing libraries of novel compounds in high-throughput screening and lead optimization programs.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the production of client-specific target molecules.
• Chemical Biology Probes: Utilized in the development of specialized probes for studying enzyme mechanisms and biological interactions.
• Academic Research: A valuable reagent for universities and research institutes exploring new heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	(4-Oxo-3,4,5,6,7,8-Hexahydro-Benzo[4,5]Thieno[2,3-D]Pyrimidin-2-Yl)-Acetonitrile
CAS No.	568543-67-9
Molecular Formula	C₁₃H₁₁N₃OS
Molecular Weight	257.31 g/mol
Synonyms	2-(4-Oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)acetonitrile; 2-(4-Oxo-5,6,7,8-tetrahydro-3H-benzo[4,5]thieno[2,3-d]pyrimidin-2-yl)acetonitrile; Hexahydro-Benzo[4,5]Thieno[2,3-D]Pyrimidin-2-Yl-Acetonitrile; 568543-67-9; (4-Oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)acetonitrile; Thienopyrimidine acetonitrile derivative
EINECS	Contact for details

Quality Control

Our (4-Oxo-3,4,5,6,7,8-Hexahydro-Benzo[4,5]Thieno[2,3-D]Pyrimidin-2-Yl)-Acetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and consistency for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.