Description

1-(7-Bromo-2,3-Dihydro-Pyrido[3,2-B][1,4]Oxazin-4-Yl)-Ethanone is a high-purity, advanced pharmaceutical intermediate characterized by its fused heterocyclic structure containing bromine and a ketone functional group. This compound is critical for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of potential drug candidates, especially for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new chemical entities.
• Organic Synthesis Reagent: Acts as a versatile precursor for further functionalization via cross-coupling reactions, leveraging the reactive bromine substituent.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of clinical trial materials and non-commercial scale APIs.
• Academic Research: Utilized in university and institutional laboratories for investigating novel heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	1-(7-Bromo-2,3-Dihydro-Pyrido[3,2-B][1,4]Oxazin-4-Yl)-Ethanone
CAS No.	566158-30-3
Molecular Formula	C9H7BrN2O2
Molecular Weight	255.07 g/mol
Synonyms	1-(7-Bromo-2,3-dihydro-4H-pyrido[3,2-b][1,4]oxazin-4-yl)ethanone; 7-Bromo-4-acetyl-2,3-dihydro-4H-pyrido[3,2-b][1,4]oxazine; Ethanone, 1-(7-bromo-2,3-dihydro-4H-pyrido[3,2-b][1,4]oxazin-4-yl)-; 4-Acetyl-7-bromo-2,3-dihydro-4H-pyrido[3,2-b][1,4]oxazine; 566158-30-3; 7-Bromo-4-acetyl-2,3-dihydro-pyrido[3,2-b][1,4]oxazine
EINECS	Contact for details

Quality Control

Our 1-(7-Bromo-2,3-Dihydro-Pyrido[3,2-B][1,4]Oxazin-4-Yl)-Ethanone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to ISO 9001 standards, and our quality protocols are designed to meet the stringent requirements of the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.