Description

1-[5-(Trifluoromethyl)Pyridin-2-Yl]Piperidin-4-Amine is a high-value, nitrogen-containing heterocyclic compound featuring a trifluoromethylpyridine core, a structure of significant interest in modern synthetic chemistry. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block for the development of novel active ingredients. It is primarily needed by R&D scientists and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) targeted research.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the biological activity of the trifluoromethylpyridine moiety.
• Ligand Synthesis: Serves as a precursor for creating complex ligands used in catalysis and material science applications.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, functionalized piperidine derivatives.
• Material Science: Potential monomer or additive in the development of advanced polymers and functional materials.

Basic Information

Product Name	1-[5-(Trifluoromethyl)Pyridin-2-Yl]Piperidin-4-Amine
CAS No.	565453-20-5
Molecular Formula	C11H14F3N3
Molecular Weight	245.25 g/mol
Synonyms	4-Amino-1-[5-(trifluoromethyl)-2-pyridinyl]piperidine; 1-(5-(Trifluoromethyl)pyridin-2-yl)piperidin-4-amine; 2-(4-Aminopiperidin-1-yl)-5-(trifluoromethyl)pyridine; Piperidin-4-amine, 1-[5-(trifluoromethyl)-2-pyridinyl]-; 565453-20-5
EINECS	Contact for details

Quality Control

Our 1-[5-(Trifluoromethyl)Pyridin-2-Yl]Piperidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.