Description

Spiro[Indolizine-1(5H),2-Oxirane] (9Ci) is a specialized spirocyclic organic compound featuring a fused indolizine and oxirane (epoxide) ring system, serving as a high-value synthetic intermediate. This unique molecular architecture makes it a critical building block for constructing complex heterocyclic frameworks in advanced pharmaceutical and agrochemical research. It is essential for medicinal chemists and R&D professionals engaged in developing novel active ingredients, particularly in the synthesis of potential drug candidates and high-performance crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel bioactive molecules, particularly for central nervous system (CNS) and anti-infective drug discovery programs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action, leveraging its spirocyclic core.
• Material Science: Serves as a monomer or cross-linking agent in the research of advanced polymers with specific thermal or optical properties.
• Organic Synthesis Building Block: Utilized in academic and industrial R&D for constructing complex natural product analogs and other intricate heterocyclic compounds.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes to study biological pathways and enzyme functions.

Basic Information

Product Name	Spiro[Indolizine-1(5H),2-Oxirane] (9Ci)
CAS No.	564478-29-1
Molecular Formula	C9H7NO
Molecular Weight	145.16 g/mol
Synonyms	Spiro[indolizine-1(5H),2'-oxirane]; 1,5-Dihydrospiro[indolizine-1,2'-oxirane]; 1,5-Dihydro-2H-spiro[indolizine-1,2'-oxirane]; Spiro[1,5-dihydroindolizine-1,2'-oxirane]; 564478-29-1; Spiro(indolizine-1(5H),2-oxirane); Spirocyclic indolizine-oxirane
EINECS	Contact for details

Quality Control

Our Spiro[Indolizine-1(5H),2-Oxirane] (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed under an inert atmosphere if long-term storage is required to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.