Description

2,8-Diaza-Spiro[4.5]Decane-2-Carboxylic Acid tert-Butyl Ester is a high-value, nitrogen-containing spirocyclic building block used in advanced organic synthesis. This compound is critical for medicinal chemistry research, serving as a versatile scaffold for the development of novel pharmaceutical candidates. It is primarily sought after by R&D teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in central nervous system (CNS) and metabolic disease research.
• Medicinal Chemistry Scaffold: Utilized as a privileged spirocyclic structure in fragment-based drug discovery and lead optimization programs.
• Agrochemical Synthesis: Intermediate in the development of novel herbicides, fungicides, and insecticides with complex mode-of-action profiles.
• Chemical Biology Probe: Used to create tool compounds for studying enzyme function and biological pathways.
• Ligand Synthesis: Serves as a precursor for chiral ligands and catalysts used in asymmetric synthesis.
• Academic & Contract Research: Essential reagent for universities and CROs conducting cutting-edge synthetic methodology and heterocyclic chemistry research.

Basic Information

Product Name	2,8-Diaza-Spiro[4.5]Decane-2-Carboxylic Acid tert-Butyl Ester
CAS No.	562858-09-7
Molecular Formula	C13H24N2O2
Molecular Weight	240.34 g/mol
Synonyms	tert-Butyl 2,8-diaza-spiro[4.5]decane-2-carboxylate; 2,8-Diaza-spiro[4.5]decane-2-carboxylic acid 1,1-dimethylethyl ester; 2-(tert-Butoxycarbonyl)-2,8-diaza-spiro[4.5]decane; 2,8-Diaza-spiro[4.5]decane-2-carboxylic acid tert-butyl ester; Boc-2,8-diaza-spiro[4.5]decane; 2-Boc-2,8-diaza-spiro[4.5]decane; 2,8-Diazaspiro[4.5]decane-2-carboxylic acid, 1,1-dimethylethyl ester; 2-(tert-Butoxycarbonyl)-2,8-diazaspiro[4.5]decane
EINECS	Contact for details

Quality Control

Our 2,8-Diaza-Spiro[4.5]Decane-2-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.