Description

(9H-Fluoren-9-Yl)Methyl 3-Bromo-4-Oxopiperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its reactive bromo and oxo functional groups. This compound is essential for facilitating complex synthetic transformations, particularly in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Peptide Mimetics & PROTACs: Used in the construction of peptide-like structures and Proteolysis-Targeting Chimeras (PROTACs) due to its piperidine scaffold and versatile handle for further functionalization.
• Agrochemical Research: Serves as a precursor in the development of new herbicides and pesticides with novel modes of action.
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical raw material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	(9H-Fluoren-9-Yl)Methyl 3-Bromo-4-Oxopiperidine-1-Carboxylate
CAS No.	562827-16-1
Molecular Formula	C21H20BrNO3
Molecular Weight	414.29 g/mol
Synonyms	Fmoc-3-bromo-4-oxopiperidine; 1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-bromo-4-piperidinone; 3-Bromo-1-(((9H-fluoren-9-yl)methoxy)carbonyl)piperidin-4-one; 3-Bromo-4-oxo-1-piperidinecarboxylic acid 9H-fluoren-9-ylmethyl ester; 3-Bromo-N-Fmoc-4-piperidone; 1-Fmoc-3-bromo-4-piperidone; 3-Bromo-1-((((9H-fluoren-9-yl)methoxy)carbonyl))piperidin-4-one
EINECS	Contact for details

Quality Control

Our (9H-Fluoren-9-Yl)Methyl 3-Bromo-4-Oxopiperidine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity suitable for sensitive pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.