Description

Furo[2,3-b]pyridine-5-carboxamide, N-[(4-chlorophenyl)methyl]-4,7-dihydro-2-(4-hydroxybutyl)-7-methyl-4-oxo- is a high-purity, complex heterocyclic organic compound serving as a critical advanced intermediate in modern pharmaceutical research and development. Its intricate molecular architecture, featuring fused furopyridine and carboxamide functionalities, makes it a valuable scaffold for synthesizing novel active pharmaceutical ingredients (APIs). This compound is essential for medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries, particularly those focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly in exploratory and preclinical development stages.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of lead compounds.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of target molecules in API manufacturing.
• Biochemical Tool Compound: Potential use in biological assays to study specific enzyme inhibition or receptor modulation, aiding in target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this specialized intermediate.

Basic Information

Product Name	Furo[2,3-b]pyridine-5-carboxamide, N-[(4-chlorophenyl)methyl]-4,7-dihydro-2-(4-hydroxybutyl)-7-methyl-4-oxo-
CAS No.	562101-79-5
Molecular Formula	C20H21ClN2O4
Molecular Weight	388.85 g/mol
Synonyms	N-[(4-Chlorophenyl)methyl]-4,7-dihydro-2-(4-hydroxybutyl)-7-methyl-4-oxofuro[2,3-b]pyridine-5-carboxamide; 4-Oxo-N-[(4-chlorophenyl)methyl]-4,7-dihydro-2-(4-hydroxybutyl)-7-methylfuro[2,3-b]pyridine-5-carboxamide; Furo[2,3-b]pyridine-5-carboxamide derivative (CAS 562101-79-5); 562101-79-5; UNII-8I4N7Z5P3S
EINECS	Contact for details

Quality Control

Our production of Furo[2,3-b]pyridine-5-carboxamide, N-[(4-chlorophenyl)methyl]-4,7-dihydro-2-(4-hydroxybutyl)-7-methyl-4-oxo- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.