Description

Furo[2,3-B]Pyridine-5-Carboxamide, 2-(Chloromethyl)-n-[(4-Chlorophenyl)Methyl]-4,7-Dihydro-4-Oxo-7-Phenyl- is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, inflammatory diseases, or oncology.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with improved efficacy and safety profiles.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, non-commercial compounds for preclinical and clinical trial material supply.
• Chemical Biology Probes: Can be utilized to develop tool compounds for investigating biological pathways and target validation.

Basic Information

Product Name	Furo[2,3-B]Pyridine-5-Carboxamide, 2-(Chloromethyl)-n-[(4-Chlorophenyl)Methyl]-4,7-Dihydro-4-Oxo-7-Phenyl-
CAS No.	562101-08-0
Molecular Formula	C22H18Cl2N2O3
Molecular Weight	429.30 g/mol
Synonyms	2-(Chloromethyl)-N-[(4-chlorophenyl)methyl]-4,7-dihydro-4-oxo-7-phenylfuro[2,3-b]pyridine-5-carboxamide; 7-Phenyl-2-(chloromethyl)-N-[(4-chlorophenyl)methyl]-4,7-dihydro-4-oxofuro[2,3-b]pyridine-5-carboxamide; Furo[2,3-b]pyridine-5-carboxamide, 2-(chloromethyl)-N-[(4-chlorophenyl)methyl]-4,7-dihydro-4-oxo-7-phenyl-; 562101-08-0; UNII-8Q8QH7U7F1
EINECS	Contact for details

Quality Control

Our Furo[2,3-B]Pyridine-5-Carboxamide intermediate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP starting material applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.