Description

Furo[2,3-B]Pyridine-5-Carboxamide, 2-(Chloromethyl)-n-[(4-Chlorophenyl)Methyl]-4,7-Dihydro-4-Oxo-7-Propyl- is a high-value, synthetically complex heterocyclic compound that serves as a critical pharmaceutical intermediate and research chemical. Its unique fused-ring structure, featuring both furopyridine and carboxamide functionalities, makes it a versatile building block for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). This compound is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in synthesizing targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold or derivatization point for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Chemical Biology Probe: Serves as a tool compound for investigating biological pathways and target validation in early-stage drug discovery.
• Custom Synthesis Building Block: Employed by contract research and manufacturing organizations (CROs/CMOs) for the production of bespoke molecules for client projects.
• Reference Standard: Supplied as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	Furo[2,3-B]Pyridine-5-Carboxamide, 2-(Chloromethyl)-n-[(4-Chlorophenyl)Methyl]-4,7-Dihydro-4-Oxo-7-Propyl-
CAS No.	562101-07-9
Molecular Formula	C19H18Cl2N2O2
Molecular Weight	377.26 g/mol
Synonyms	2-(Chloromethyl)-N-[(4-chlorophenyl)methyl]-4,7-dihydro-4-oxo-7-propylfuro[2,3-b]pyridine-5-carboxamide; 7-Propyl-2-(chloromethyl)-N-[(4-chlorophenyl)methyl]-4,7-dihydro-4-oxofuro[2,3-b]pyridine-5-carboxamide; Furo[2,3-b]pyridine-5-carboxamide, 2-(chloromethyl)-N-[(4-chlorophenyl)methyl]-4,7-dihydro-4-oxo-7-propyl-; CAS 562101-07-9
EINECS	Contact for details

Quality Control

Our Furo[2,3-B]Pyridine-5-Carboxamide derivative is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization using advanced techniques like HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and pre-clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.