Description

Furo[2,3-B]Pyridine-5-Carboxylic Acid, 2-Formyl-4,7-Dihydro-7-Methyl-4-Oxo-, Ethyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research areas targeting specific enzymatic pathways. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new therapeutic agents. The precise molecular architecture of this ester makes it a valuable building block for medicinal chemists.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in oncology and antiviral research.
• Medicinal Chemistry Research: Used as a sophisticated building block for structure-activity relationship (SAR) studies and lead optimization.
• Organic Synthesis: Employed in complex multi-step syntheses to construct fused heterocyclic systems of biological interest.
• Biochemical Research: May be utilized as a substrate or inhibitor in enzymatic studies due to its specific structural motifs.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP production of clinical trial materials.
• Academic Research: Used in university and institutional labs for pioneering research in synthetic methodology and drug discovery.

Basic Information

Product Name	Furo[2,3-B]Pyridine-5-Carboxylic Acid, 2-Formyl-4,7-Dihydro-7-Methyl-4-Oxo-, Ethyl Ester
CAS No.	562100-66-7
Molecular Formula	C13H13NO5
Molecular Weight	263.25 g/mol
Synonyms	Ethyl 2-Formyl-4,7-dihydro-7-methyl-4-oxofuro[2,3-b]pyridine-5-carboxylate; 5-Carbethoxy-2-formyl-4,7-dihydro-7-methyl-4-oxofuro[2,3-b]pyridine; Furo[2,3-b]pyridine-5-carboxylic acid, 2-formyl-4,7-dihydro-7-methyl-4-oxo-, ethyl ester; 2-Formyl-7-methyl-4-oxo-4,7-dihydrofuro[2,3-b]pyridine-5-carboxylic acid ethyl ester; Ethyl 2-formyl-7-methyl-4-oxo-4,7-dihydrofuro[2,3-b]pyridine-5-carboxylate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is subjected to rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development and cGMP manufacturing needs with appropriate documentation and regulatory starting material guidance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.