Description

5-(Chloromethyl)Nicotinonitrile is a versatile and high-value pyridine derivative building block, essential for advanced organic synthesis. Its bifunctional structure, featuring both a reactive chloromethyl group and a nitrile-substituted pyridine ring, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the pyridine core's bioactivity.
• Ligand and Catalyst Precursor: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials or metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Manufacturing: A crucial reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic and R&D Laboratories: Used in methodological development and exploratory chemistry for creating novel heterocyclic compounds.

Basic Information

Product Name	5-(Chloromethyl)Nicotinonitrile
CAS No.	562074-59-3
Molecular Formula	C7H5ClN2
Molecular Weight	152.58 g/mol
Synonyms	5-(Chloromethyl)pyridine-3-carbonitrile; 3-Cyano-5-(chloromethyl)pyridine; Nicotinonitrile, 5-(chloromethyl)-; 5-Chloromethylnicotinonitrile; 3-Pyridinecarbonitrile, 5-(chloromethyl)-; 5-(Chloromethyl)-3-cyanopyridine
EINECS	Contact for details

Quality Control

Our 5-(Chloromethyl)Nicotinonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements of research and process development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.