Description

Spiro[4.5]Dec-3-En-2-One, 1,4,6-Trimethyl-, (1R,5R,6R)-Rel- (9Ci) is a high-purity, stereochemically defined spirocyclic ketone building block of significant interest in advanced organic synthesis. Its rigid, three-dimensional structure and specific stereochemistry make it a valuable intermediate for constructing complex molecular architectures with precise spatial orientation. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, asymmetric synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its spirocyclic core can contribute to unique biological activity and environmental stability.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of chiral ligands and organocatalysts used in enantioselective transformations.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating polymers with specific thermal or mechanical properties due to its rigid backbone.
• Fragrance & Flavor Chemistry: Potential intermediate for synthesizing complex, musky, or woody odorant molecules owing to its spirocyclic ketone structure.
• Academic & Process Chemistry: Employed in methodological studies and scale-up process development for complex organic molecule manufacturing.

Basic Information

Product Name	Spiro[4.5]Dec-3-En-2-One, 1,4,6-Trimethyl-, (1R,5R,6R)-Rel- (9Ci)
CAS No.	557785-47-4
Molecular Formula	C13H20O
Molecular Weight	192.30 g/mol
Synonyms	rel-(1R,5R,6R)-1,4,6-Trimethylspiro[4.5]dec-3-en-2-one; (1R,5R,6R)-1,4,6-Trimethylspiro[4.5]dec-3-en-2-one (relative); 1,4,6-Trimethylspiro[4.5]dec-3-en-2-one; Spiro[4.5]dec-3-en-2-one, 1,4,6-trimethyl-, (1R,5R,6R)-rel-; Trimethylspirodecenone
EINECS	Contact for details

Quality Control

Our Spiro[4.5]Dec-3-En-2-One, 1,4,6-Trimethyl-, (1R,5R,6R)-Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound may be sensitive to prolonged exposure to air and moisture; keep container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.