Description

(2-Chloro-3-Pyridinyl)(2,3-Dihydro-1H-Indol-1-Yl)-Methanone is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for creating new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the production of modern pesticides and herbicides, where its specific molecular framework contributes to the efficacy of the final product.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Employed in scale-up and pilot plant studies for the commercial manufacturing of complex organic molecules.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) engaged in custom synthesis projects.

Basic Information

Product Name	(2-Chloro-3-Pyridinyl)(2,3-Dihydro-1H-Indol-1-Yl)-Methanone
CAS No.	557781-56-3
Molecular Formula	C14H11ClN2O
Molecular Weight	258.70 g/mol
Synonyms	1-(2-Chloro-3-pyridinecarbonyl)indoline; (2-Chloro-3-pyridinyl)(2,3-dihydro-1H-indol-1-yl)methanone; 2-Chloro-N-(2,3-dihydro-1H-indol-1-yl)nicotinamide; 2-Chloronicotinic acid indoline-1-yl amide; (2-Chloro-pyridin-3-yl)-(2,3-dihydro-1H-indol-1-yl)-methanone; Indoline-1-carboxylic acid (2-chloro-3-pyridyl)amide
EINECS	Contact for details

Quality Control

Our (2-Chloro-3-Pyridinyl)(2,3-Dihydro-1H-Indol-1-Yl)-Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.