Description

Dihydro-Spiro[8-Azabicyclo[3.2.1]Octane-3,2'(3'H)-Furan] is a complex, nitrogen-containing spirocyclic compound with the CAS number 556062-54-5. This advanced pharmaceutical intermediate is valued for its unique bridged bicyclic and spirocyclic architecture, which provides a rigid three-dimensional framework crucial for modern drug discovery. It is primarily sought by research and development teams in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and other therapeutic areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially for neurological and psychiatric applications.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• API Development: Serves as a core structural motif in the development of novel Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Utilized in the design of molecular probes to study biological pathways and protein functions.
• Asymmetric Synthesis: Acts as a chiral precursor or template in stereoselective synthesis due to its complex, defined stereochemistry.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for pharmaceutical clients.

Basic Information

Product Name	Dihydro-Spiro[8-Azabicyclo[3.2.1]Octane-3,2'(3'H)-Furan]
CAS No.	556062-54-5
Molecular Formula	C9H13NO
Molecular Weight	151.21 g/mol
Synonyms	8-Azabicyclo[3.2.1]octane-3,2'-furan dihydro derivative; 2',3'-Dihydrospiro[8-azabicyclo[3.2.1]octane-3,2'-furan]; Dihydrospiro[8-azabicyclo[3.2.1]octane-3,2'(3'H)-furan]; Tropane-fused dihydrofuran; Spiro[tropane-3,2'-oxolane]; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Dihydro-Spiro[8-Azabicyclo[3.2.1]Octane-3,2'(3'H)-Furan] is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and pre-clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.