Description

1-(4-Hydroxyphenyl)-3-(2,3,4-Trimethoxyphenyl)-2-Propen-1-One is a high-purity synthetic chalcone derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical building block and a versatile scaffold for developing novel bioactive molecules. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for its potential as a key intermediate in drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, and metabolic disorders.
• Chemical Biology Research: Used as a molecular probe or scaffold to study protein-ligand interactions and enzyme inhibition mechanisms.
• Agrochemical Development: Serves as an intermediate for creating new plant protection agents with potential fungicidal or herbicidal activity.
• Material Science: Investigated as a monomer or precursor for specialty polymers and advanced organic materials with specific optical properties.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting fundamental research on chalcone chemistry and its applications.

Basic Information

Product Name	1-(4-Hydroxyphenyl)-3-(2,3,4-Trimethoxyphenyl)-2-Propen-1-One
CAS No.	556028-14-9
Molecular Formula	C18H18O5
Molecular Weight	314.33 g/mol
Synonyms	2-Propen-1-one, 1-(4-hydroxyphenyl)-3-(2,3,4-trimethoxyphenyl)-; 3-(2,3,4-Trimethoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one; 4-Hydroxy-2',3',4'-trimethoxychalcone; 2',3',4'-Trimethoxy-4-hydroxychalcone; Chalcone derivative 556028-14-9; (E)-1-(4-Hydroxyphenyl)-3-(2,3,4-trimethoxyphenyl)prop-2-en-1-one; Light-sensitive chalcone intermediate
EINECS	Contact for details

Quality Control

Our 1-(4-Hydroxyphenyl)-3-(2,3,4-Trimethoxyphenyl)-2-Propen-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent potential oxidation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.