Description

1H-Pyrrolo[2,3-B]Pyridine-3-Ethanamine, 1-[(3-Methylphenyl)Sulfonyl]- is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a critical intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process R&D, and the synthesis of targeted small molecule therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization programs due to its privileged pyrrolopyridine scaffold.
• Process Chemistry & Scale-up: Employed in route scouting and pilot-scale synthesis for the production of advanced pharmaceutical intermediates (APIs).
• Bioconjugation & Probe Development: The functional amine group allows for its use in creating labeled compounds for biochemical assays and diagnostic probes.
• Agrochemical Research: Potential application as a building block for novel crop protection agents and pesticides.
• Material Science Precursor: Can be utilized in the synthesis of organic electronic materials and ligands for catalytic systems.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-3-Ethanamine, 1-[(3-Methylphenyl)Sulfonyl]-
CAS No.	554453-16-6
Molecular Formula	C16H17N3O2S
Molecular Weight	315.39 g/mol
Synonyms	1-[(3-Methylphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridine-3-ethanamine; 1-(m-Tolylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-ethanamine; 3-(2-Aminoethyl)-1-(3-methylphenyl)sulfonyl-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine-3-ethanamine, 1-[(3-methylphenyl)sulfonyl]-; 1-Tosyl-1H-pyrrolo[2,3-b]pyridine-3-ethanamine (related); 7-Azaindole-3-ethylamine derivative; Sulfonated pyrrolopyridine ethylamine
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-3-Ethanamine, 1-[(3-Methylphenyl)Sulfonyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP standards where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.