Description

L-Leucine, n-[(1R)-1-(2,4-Difluorophenyl)-2-Oxo-2-[[2-(Phenylmethoxy)Phenyl]Amino]Ethyl]-, Methyl Ester (9Ci) is a sophisticated chiral organic compound designed for advanced chemical synthesis. This molecule matters as a high-value pharmaceutical intermediate or research chemical, offering a precise structural scaffold for developing novel active ingredients. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for drug discovery and process chemistry applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those targeting specific biological pathways.
• Protease Inhibitor Research: Potential precursor or analog in the development of enzyme inhibitors due to its peptide-like backbone and ester functionality.
• Chemical Biology Probe: Used in research to study enzyme-substrate interactions or as a tagged molecule for biochemical assays.
• Process Chemistry & Scale-Up: Serves as a critical intermediate during the optimization and manufacturing scale-up of new chemical entities.
• Asymmetric Synthesis: Utilized in chiral synthesis to introduce specific stereochemistry into more complex molecular architectures.
• Academic & Institutional Research: Employed in university and institutional labs for methodological studies in organic and medicinal chemistry.

Basic Information

Product Name	L-Leucine, n-[(1R)-1-(2,4-Difluorophenyl)-2-Oxo-2-[[2-(Phenylmethoxy)Phenyl]Amino]Ethyl]-, Methyl Ester (9Ci)
CAS No.	554448-66-7
Molecular Formula	C25H24F2N2O4
Molecular Weight	454.47 g/mol
Synonyms	(2R)-2-[(2,4-Difluorophenyl)(formamido)methyl]-N-[2-(benzyloxy)phenyl]-4-methylpentanamide methyl ester; Methyl (2R)-2-[(2,4-difluorophenyl)(formamido)methyl]-4-methyl-N-[2-(phenylmethoxy)phenyl]pentanamide; L-Leucine, N-[(1R)-1-(2,4-difluorophenyl)-2-oxo-2-[[2-(phenylmethoxy)phenyl]amino]ethyl]-, methyl ester; 554448-66-7; 9CI-554448-66-7; SCHEMBL23358277; AKOS040759310; F2198-7248
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, NMR, and MS for identity confirmation and purity verification. Certificates of Analysis (COA) detailing batch-specific results are available upon request. Our quality management system supports production suitable for research and development under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.