Description

3-Bromo-5-(4-Methoxybenzyloxy)Pyridine is a high-purity, functionalized pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, featuring both a bromo substituent for cross-coupling reactions and a protected benzyloxy group, enabling precise molecular construction. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science Research: Used in the creation of organic ligands for catalysis and functional organic materials like liquid crystals.
• Cross-Coupling Reactions: The bromine atom facilitates Suzuki, Stille, and Negishi couplings for carbon-carbon bond formation.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes and tool compounds for biological target validation.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific, multi-functional heterocycles.

Basic Information

Item	Details
Product Name	3-Bromo-5-(4-Methoxybenzyloxy)Pyridine
CAS No.	552331-73-4
Molecular Formula	C13H12BrNO2
Molecular Weight	294.15 g/mol
Synonyms	3-Bromo-5-[(4-methoxyphenyl)methoxy]pyridine; 5-[(4-Methoxybenzyl)oxy]-3-bromopyridine; 3-Bromo-5-(p-methoxybenzyloxy)pyridine; 3-Bromo-5-(4-Methoxybenzyloxy)Pyridine; 552331-73-4; 3-Br-5-(4-MeOBnO)Py
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-(4-Methoxybenzyloxy)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if opened for prolonged periods. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.