Description

3-Bromo-5-(2-Pyridin-4-Yl-Vinyl)-Pyridine is a high-value brominated pyridine derivative featuring a conjugated vinyl linker, making it a versatile and critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals, agrochemicals, and functional materials, where its specific halogenated structure enables precise molecular construction. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and electronic components.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated heterocyclic core.
• Material Science & OLED Development: Acts as an electron-transporting or host material precursor in the manufacture of organic light-emitting diodes (OLEDs) and other electronic materials due to its conjugated system.
• Ligand Synthesis for Catalysis: Employed in the preparation of complex ligands for transition metal catalysts used in cross-coupling and other organic transformations.
• Chemical Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Life Science Reagents: Utilized in the development of fluorescent probes, biomarkers, and other diagnostic reagents.

Basic Information

Product Name	3-Bromo-5-(2-Pyridin-4-Yl-Vinyl)-Pyridine
CAS No.	552330-28-6
Molecular Formula	C12H9BrN2
Molecular Weight	261.12 g/mol
Synonyms	3-Bromo-5-[(E)-2-(pyridin-4-yl)ethenyl]pyridine; 4-[2-(5-Bromo-3-pyridinyl)ethenyl]pyridine; 3-Bromo-5-(2-(4-pyridyl)vinyl)pyridine; 5-Bromo-3-(2-pyridin-4-yl-vinyl)-pyridine; 3-Bromo-5-styrylpyridine (partial); Pyridine, 3-bromo-5-[2-(4-pyridinyl)ethenyl]-; (E)-3-Bromo-5-(2-(pyridin-4-yl)vinyl)pyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-(2-Pyridin-4-Yl-Vinyl)-Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be performed under subdued lighting or in amber glass containers when possible.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.