Description

5-Bromo-2-(2-{[2-(Trimethylsilyl)Ethoxy]Methoxypropan-2-Yl)Pyridine is a high-value, organosilicon-protected pyridine derivative used as a sophisticated synthetic intermediate. This compound matters for enabling complex multi-step organic syntheses, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, especially those targeting the central nervous system (CNS).
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides requiring specific halogenated pyridine motifs.
• Ligand Precursor: Serves as a starting material for the preparation of specialized ligands used in catalysis and material science.
• Functional Material Development: Employed in the creation of organic electronic materials, such as those for OLEDs, due to its modified pyridine core.
• Academic & Contract Research: Essential reagent for methodological studies in organic chemistry, particularly in cross-coupling and protection/deprotection strategies.

Basic Information

Product Name	5-Bromo-2-(2-{[2-(Trimethylsilyl)Ethoxy]Methoxypropan-2-Yl)Pyridine
CAS No.	552287-64-6
Molecular Formula	C14H24BrNO2Si
Molecular Weight	346.34 g/mol
Synonyms	5-Bromo-2-(2-{[2-(trimethylsilyl)ethoxy]methoxy}propan-2-yl)pyridine; 2-(5-Bromo-2-pyridyl)-2-[(2-trimethylsilylethoxy)methoxy]propane; 5-Bromo-2-[2-({[2-(trimethylsilyl)ethoxy]methoxy})propan-2-yl]pyridine; 552287-64-6; Pyridine, 5-bromo-2-[2-[[[2-(trimethylsilyl)ethoxy]methoxy]methyl]-2-propyl]-; SEM-protected 5-Bromo-2-(2-hydroxypropan-2-yl)pyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(2-{[2-(Trimethylsilyl)Ethoxy]Methoxypropan-2-Yl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are available for review and are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.