Description

7-Trifluoromethyl-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester is a high-value fluorinated heterocyclic building block essential for advanced organic synthesis. This compound is prized for its role in introducing the trifluoromethyl group and benzo[b]thiophene scaffold into target molecules, significantly altering their physicochemical properties. It is a critical intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-inflammatory agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialized polymers and organic electronic materials.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry: A versatile substrate for further functionalization in fluorochemical research, enabling the exploration of structure-activity relationships.

Basic Information

Product Name	7-Trifluoromethyl-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester
CAS No.	550998-55-5
Molecular Formula	C11H7F3O2S
Molecular Weight	260.23 g/mol
Synonyms	Methyl 7-(trifluoromethyl)benzo[b]thiophene-2-carboxylate; 7-(Trifluoromethyl)-1-benzothiophene-2-carboxylic acid methyl ester; 2-Methoxycarbonyl-7-trifluoromethylbenzo[b]thiophene; Benzo[b]thiophene-2-carboxylic acid, 7-(trifluoromethyl)-, methyl ester; Methyl 7-trifluoromethyl-1-benzothiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Our production of 7-Trifluoromethyl-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. Quality is verified through comprehensive analytical techniques including HPLC, GC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.