Description

7-Fluoro-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester is a high-value fluorinated heterocyclic building block essential for advanced organic synthesis. This compound is critical for introducing the benzo[b]thiophene scaffold with a fluorine substituent, enabling the fine-tuning of molecular properties in target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the fluorinated benzo[b]thiophene core imparts desirable biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or precursor for the synthesis of specialty polymers and organic electronic materials.
• Fluorine Chemistry Studies: An important substrate for investigating novel fluorination reactions and studying structure-activity relationships (SAR) in medicinal chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this specific fluorinated scaffold.

Basic Information

Product Name	7-Fluoro-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester
CAS No.	550998-54-4
Molecular Formula	C10H7FO2S
Molecular Weight	210.22 g/mol
Synonyms	Methyl 7-Fluorobenzo[b]thiophene-2-carboxylate; 7-Fluorobenzo[b]thiophene-2-carboxylic acid methyl ester; 2-Methoxycarbonyl-7-fluorobenzo[b]thiophene; 7-Fluoro-1-benzothiophene-2-carboxylic acid methyl ester; Methyl 7-fluoro-1-benzothiophene-2-carboxylate; 550998-54-4; 7-F-BT-2-COOMe
EINECS	Contact for details

Quality Control

Our 7-Fluoro-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and stringent in-process controls guarantees a reliable supply of this high-purity research chemical.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.