Description

Carbamic Acid, [(3S)-1-Methyl-5-Oxo-3-Pyrrolidinyl]-, 1,1-Dimethylethyl Ester is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a key building block for the production of complex, biologically active molecules, particularly in the pharmaceutical sector. This compound is essential for research and development chemists and process scale-up teams working on novel therapeutics, including protease inhibitors and other specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the multi-step synthesis of complex drug candidates, especially those targeting neurological and viral diseases.
• Protease Inhibitor Precursor: Serves as a foundational component in the construction of molecules designed to inhibit specific protease enzymes.
• Asymmetric Synthesis: Utilized in stereoselective reactions to introduce the (3S)-configured pyrrolidinone scaffold into target molecules.
• API Development: Employed in research, process development, and cGMP manufacturing of new chemical entities (NCEs).
• Chemical Reference Standard: Used as a high-purity standard for analytical method development and quality control in pharmaceutical laboratories.
• Academic & Industrial R&D: A valuable reagent for exploring new synthetic methodologies and reaction pathways in medicinal chemistry.

Basic Information

Product Name	Carbamic Acid, [(3S)-1-Methyl-5-Oxo-3-Pyrrolidinyl]-, 1,1-Dimethylethyl Ester
CAS No.	549531-76-2
Molecular Formula	C11H19NO3
Molecular Weight	213.27 g/mol
Synonyms	(3S)-1-Methyl-5-oxopyrrolidine-3-carboxylic acid tert-butyl ester; tert-Butyl (3S)-1-methyl-5-oxo-3-pyrrolidinecarboxylate; (3S)-1-Methyl-5-oxo-3-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester; (S)-1-Methyl-5-oxopyrrolidine-3-carboxylic acid tert-butyl ester; Boc-(S)-1-Methyl-5-oxo-3-pyrrolidinecarboxylate; (S)-tert-Butyl 1-methyl-5-oxopyrrolidine-3-carboxylate
EINECS	Contact for details

Quality Control

Our Carbamic Acid, [(3S)-1-Methyl-5-Oxo-3-Pyrrolidinyl]-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.