Description

(2S,5R)-2,5-Dimethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, stereochemically defined piperazine derivative, serving as a critical chiral building block in advanced organic synthesis. Its primary value lies in its role as a key intermediate for constructing complex molecules with precise stereochemistry, essential for developing active pharmaceutical ingredients (APIs) and other fine chemicals. This compound is particularly vital for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for process development and scale-up.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where specific stereochemistry impacts biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptidomimetic Research: Incorporated into the backbone of peptide analogs to enhance metabolic stability and bioavailability.
• Custom Chemical Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke client projects requiring stereochemical control.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	(2S,5R)-2,5-Dimethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	548762-66-9
Molecular Formula	C11H22N2O2
Molecular Weight	214.31 g/mol
Synonyms	Boc-(2S,5R)-2,5-Dimethylpiperazine; 1-Boc-(2S,5R)-2,5-Dimethylpiperazine; tert-Butyl (2S,5R)-2,5-dimethylpiperazine-1-carboxylate; (2S,5R)-1-N-Boc-2,5-dimethylpiperazine; (2S,5R)-2,5-Dimethyl-1-(tert-butoxycarbonyl)piperazine; (2S,5R)-1-(tert-Butoxycarbonyl)-2,5-dimethylpiperazine; (2S,5R)-2,5-DMP-Boc
EINECS	Contact for details

Quality Control

Our (2S,5R)-2,5-Dimethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity (typically >98%), enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.