Description

5,8-Dioxaspiro[3.4]Octane-2-Methanol is a specialized spirocyclic ether alcohol building block of significant interest in advanced organic synthesis. Its unique fused-ring structure containing both ether and alcohol functionalities makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators that require specific stereochemistry.
• Ligand and Catalyst Development: Serves as a backbone for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for synthesizing specialty polymers with tailored thermal and mechanical properties.
• Fragrance & Flavor Chemistry: Employed in the synthesis of complex, oxygenated fragrance molecules due to its spirocyclic ether structure.
• Academic & Industrial R&D: A versatile building block for methodological studies in organic chemistry, including ring-opening and functional group transformation reactions.

Basic Information

Product Name	5,8-Dioxaspiro[3.4]Octane-2-Methanol
CAS No.	545882-60-8
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	2-(Hydroxymethyl)-5,8-dioxaspiro[3.4]octane; 5,8-Dioxaspiro[3.4]octane-2-methanol; Spiro[3.4]octane-2-methanol, 5,8-dioxa-; 2-Methanol-5,8-dioxaspiro[3.4]octane
EINECS	Contact for details

Quality Control

We supply 5,8-Dioxaspiro[3.4]Octane-2-Methanol in high-purity grades suitable for research and scale-up applications. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.