Description

Carbamic Acid, [1-(Hydroxymethyl)-2,2-Dimethylpropyl]-, 1,1-Dimethylethyl Ester is a specialized carbamate derivative with a unique sterically hindered structure. This compound is valued for its role as a key protected intermediate or building block in advanced organic synthesis, particularly in pharmaceutical development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring sterically hindered amine or carbamate functionalities.
• Peptide Mimetics & Prodrug Synthesis: Used in the design and creation of peptide analogs and prodrugs where the tert-butyloxycarbonyl (Boc) and neopentyl-like structure provide specific stability and release profiles.
• Agrochemical Research: Acts as an intermediate in the development of novel herbicides, fungicides, or insecticides that utilize carbamate chemistry.
• Polymer Science: Can be employed as a monomer or modifying agent in the synthesis of specialized polyurethanes or other polymers with tailored properties.
• Chemical Biology & Proteomics: Useful as a reagent for modifying proteins or peptides, or in the synthesis of activity-based probes and other research tools.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Carbamic Acid, [1-(Hydroxymethyl)-2,2-Dimethylpropyl]-, 1,1-Dimethylethyl Ester
CAS No.	545433-63-4
Molecular Formula	C11H23NO3
Molecular Weight	217.31 g/mol
Synonyms	tert-Butyl N-(2,2-dimethyl-3-hydroxypropyl)carbamate; 3-[(tert-Butoxycarbonyl)amino]-2,2-dimethyl-1-propanol; 2,2-Dimethyl-3-[(tert-butoxycarbonyl)amino]-1-propanol; Boc-3-amino-2,2-dimethylpropanol; N-Boc-3-amino-2,2-dimethylpropan-1-ol; (3-Hydroxy-2,2-dimethylpropyl)carbamic acid tert-butyl ester; 1,1-Dimethylethyl N-[1-(hydroxymethyl)-2,2-dimethylpropyl]carbamate
EINECS	Contact for details

Quality Control

Our Carbamic Acid, [1-(Hydroxymethyl)-2,2-Dimethylpropyl]-, 1,1-Dimethylethyl Ester is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request. We support compliance with REACH, FDA guidelines, and other relevant regulatory frameworks for intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen to prevent degradation. Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.