Description

4-[6-Chloro-2-(2-(Pyridin-2-Yl)Ethoxy)Pyrimidin-4-Yl]Morpholine is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound is valued for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in kinase inhibitor development. It is essential for R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking reliable, high-quality intermediates for their synthetic routes.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of targeted therapeutic agents, especially kinase inhibitors.
• Biochemical Research: Used as a reference standard or a starting material in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Process Chemistry: Serves as a key building block in the scale-up and optimization of API manufacturing processes under cGMP conditions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development of novel drug candidates.
• Academic Research: Utilized in university and institutional labs for exploratory synthesis and the development of new synthetic methodologies.

Basic Information

Product Name	4-[6-Chloro-2-(2-(Pyridin-2-Yl)Ethoxy)Pyrimidin-4-Yl]Morpholine
CAS No.	544693-01-8
Molecular Formula	C15H17ClN4O2
Molecular Weight	320.78 g/mol
Synonyms	4-(6-Chloro-2-((2-pyridinyloxy)ethyl)pyrimidin-4-yl)morpholine; 4-[6-Chloro-2-[2-(2-pyridinyl)ethoxy]-4-pyrimidinyl]morpholine; Morpholine, 4-[6-chloro-2-[2-(2-pyridinyl)ethoxy]-4-pyrimidinyl]-; 544693-01-8; UNII-6V2Q8K8Q0M; 6V2Q8K8Q0M
EINECS	Contact for details

Quality Control

Our 4-[6-Chloro-2-(2-(Pyridin-2-Yl)Ethoxy)Pyrimidin-4-Yl]Morpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.