Description

2-Chloro-4-Iodo-Nicotinic Acid is a halogenated nicotinic acid derivative that serves as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its core value lies in providing a functionalized pyridine scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2-Chloro-4-Iodo-Nicotinic Acid
CAS No.	544671-78-5
Molecular Formula	C6H3ClINO2
Molecular Weight	283.45 g/mol
Synonyms	2-Chloro-4-iodopyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 2-chloro-4-iodo-; 4-Iodo-2-chloronicotinic acid; 2-Chloro-4-iodonicotinic acid; 2-Chloro-4-iodo-3-pyridinecarboxylic acid; 2-Chloro-4-iodopyridine-3-carboxylate; 544671-78-5 (CAS)
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Iodo-Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed in a dry and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.